Bioconjugation Development Scientist - (Horsham, PA)

Develop and advance projects for Antibody Drug Conjugates through preclinical and clinical stage. Functions: *** Advance development of multiple antibody drug conjugate programs. *** Apply Design of Experiments, Quality by Design, and Failure Modes and Effects Analysis principles to support process understanding, scale-up, and specification setting. *** Perform various analytical characterization and chromatography purification techniques size-exclusion chromatography, hydrophobic interaction chromatography, sodium dodecyl sulfate polyacrylamide gel electrophoresis, ion exchange, etc. and interpret results. *** Develop and execute process characterization strategies to identify Critical Quality Attributes, Proven Acceptable Ranges, Critical Process Parameters, and Quality Risk Assessments to support process validation prior to Biologics License Application filings.