Animal Pharmacologist - Jupiter, Florida - (Jupiter, FL)

Animal Pharmacologist Summary The Animal Pharmacologist position will be responsible for in vivo studies in mice and rats. The successful applicant will have a proven work history in generating hypotheses and using molecular in vitro/ex vivo experimental approaches to support lead drug testing. Studies will include administration of agent via various routes and collecting and analyzing tissue samples and animal behavior. Sample testing will include transcript analysis, histology, fluorescence in situ hybridization of collected tissue samples and muscle strength and myotonia in mouse models. Design and analysis of RNA-seq experiments is highly desirable. Required functions Independently design and supervise the conduct of cell and molecular in vitro/ex vivo experimental approaches supporting hypothesis testing and predictive toxicology (for both routine and novel experimental platforms) Conduct PK/PD and efficacy studies in mice and rats Run tolerability studies Collect blood